4th International Conference on Primary Health Care & 2nd Euro Nursing Congress
September 15-16 2025 | Virtual Event
Bernd Blobel
University of Regensburg, Germany
Healthcare systems worldwide are undergoing rapid organizational, methodological, and
technological transformation towards personalized, preventive, predictive, participative precision
(5P) medicine ecosystems. These ecosystems integrate individual health status, genetic
and genomic predispositions, and personal social, occupational, environmental, and
behavioral contexts. Designing and managing such complex, interdisciplinary, and dynamic
ecosystems requires formal and consistent representation of all system components from
the perspective of every actor, including the subject of care. As actors from diverse domains
possess different education, skills, methodologies, and terminologies, interoperability must
progress beyond data sharing to knowledge sharing. To achieve this, each use case must
be formally represented both structurally and functionally. The design, implementation, and
management of intelligent and ethical ecosystems must therefore adopt a system-theoretical,
architecture-centered, ontology-based, and policy-driven approach developed by the
author over the past 30 years. This model, now standardized as the ISO 23903 Interoperability
and Integration Reference Architecture, is mandated for any specification or project at ISO,
CEN, IEEE, OMG, and related bodies addressing multiple domains. It further ensures the detailed
management of security, privacy, and trust. This keynote introduces essential standards
and methodologies for building 5P medicine ecosystems, supported by practical examples.
Bernd Blobel is former Head of the German National eHealth Competence Center at the University of Regensburg
and has been instrumental in shaping global strategies for health digitalization and electronic health records.
With a background spanning Mathematics, Cybernetics, Physics, Medicine, and Informatics, he has authored
over 600 scientific publications and several books. He has represented Germany in leading standards
organizations such as HL7, ISO, CEN, IEEE, and SNOMED, and continues to contribute to international higher
education and interdisciplinary health informatics.