The compliance of gentamicin prescription in surgical patients using Hartford regimen: Clinical Audit

3rd International Congress on Surgery and Anesthesia

September 02 | Virtual Event

Ibrahim Abuelbeh

Manchester University NHS Foundation Trust UK, United Kingdom

Abstract :

Abstract:
Aims: This audit aimed to evaluate the adherence to prescribing protocols for gentamicin in
surgical patients using Hartford regimen, focusing on dose accuracy, therapeutic drug monitoring,
and level interpretation.
Methods: A two-cycle audit was conducted to assess compliance with local gentamicin
prescribing guidelines. Data were collected retrospectively from acutely admitted surgical
patients prescribed gentamicin. The first cycle included 15 patients, while the second cycle
reviewed 16 patients. Parameters analyzed included the right initial dose, post-dose level
measurement and timing, and the accuracy of interpreting therapeutic drug levels. Interventions,
including education and revised prescribing protocols, were introduced between the
two cycles to address identified deficiencies.
Results: In the first audit cycle, 60% of patients received the correct initial dose of gentamicin.
Post-dose levels were taken in 90.9% of cases, with 80% measured within the appropriate time
frame, and 75% of these levels were interpreted correctly. Hartford regimen was applied correctly
in 50% of the cases. Following interventions, the second cycle demonstrated improvements
in dose accuracy to 88% and level interpretation to 75%, though a decline was observed
in the post dose level taken to 85.7% and timing of post-dose level measurements to 66.6%.
Overall, the Hartford regimen was applied correctly in 66.6%. Persistent challenges included
inconsistent timing of therapeutic monitoring.
Conclusions: The interventions implemented resulted in significant improvements in dosing
accuracy but highlighted ongoing issues with the timing of level monitoring. Future strategies
should emphasize further education, clear handover, teaching modules and robust documentation
systems to enhance compliance and patient safety.
Biography
Ibrahim Abuelbeh is a Clinical Fellow in Urology in the United Kingdom. After earning a medical degree from
the University of Jordan, he pursued surgical training in general surgery and then in urology, gaining extensive
clinical and research experience. Passionate about improving surgical outcomes, Dr. Abuelbeh focuses on both
clinical and academic aspects. Actively involved in research and education, he strives to advance urological
techniques and patient care. Committed to continuous learning, Dr. Abuelbeh aims to contribute to the evolving
field of urology through innovation and expertise.