Metastatic Intradural Primary Spinal Osteosarcoma: A Case Report

Shreyas Thiruvengadam

Sir Char, Australia

Biography :

S Thiruvengadam is currently a surgical registrar working in the Western Australian Neurosurgery State-wide service, and has a special interest in Neuro-oncology. Having worked previously towards developing novel epi­genetic therapeutics for triple negative breast cancer, he seeks to employ its utility in the treatment of neurolog­ical malignancies previously doomed to be of poor prognoses.

Abstract :

Background: Osteosarcomas are a common primary bone neoplasm amongst adolescents and possess a significant metastatic potential culminating in treatment resistance and poor prognosis. Herein presented is the first documented case of lumbosacral intra-dural metas­tasis of a primary osteosarcoma in a young patient, possibly via intra-dural dissemination following pinhole durotomy in a prior thoracic spondylectomy.

Conclusion: Osteosarcomas remain a difficult pathology to treat, particularly upon metastatic dissemination. The utility of adjuvant radiotherapy following surgical resection of osteosar­comas is increasingly evident in the reduction of local recurrence. In the context of intra-op­erative pinhole durotomies in resections of high-grade lesions, due consideration should be given to whole spine radiation, although this remains to be an evidence-free zone.